I took both of those drugs in preparation for a stem cell transplant. The dex increased my appetite and I gained 20 pounds (all of which I lost during the transplant). It also made me very emotional, which I had never been before, and the effect persists after three years.
I have only two side effects from the bortezomib, which I continue to take every two weeks (with no other drug)—low platelet count and fatigue.